HIGH GENETIC DIVERSITY AMONG BREEDING RED-BACKED SHRIKES LANIUS COLLURIO IN THE WESTERN PALEARCTIC




Structure, Function, and Allosteric Regulation of the 20S Proteasome by the 11S/PA28 Family of Proteasome Activators

The proteasome, a complex multi-catalytic protease machinery, orchestrates the protein degradation essential for maintaining cellular homeostasis, and its dysregulation also underlies many different types of diseases.Its function is regulated by many different mechanisms that encompass various factors such as proteasome activators (PAs), adaptor pr

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Dynamics of compartment-specific proteomic landscapes of hepatotoxic and cholestatic models of liver fibrosis

Accumulation of extracellular matrix (ECM) in liver fibrosis is associated with changes in protein abundance and composition depending upon etiology of the underlying liver disease.Current efforts to unravel etiology-specific mechanisms and pharmacological targets rely on several models of experimental fibrosis.Here, we characterize and compare dyn

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